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Fluconazole is used for the treatment of serious fungal infections, especially of the central nervous system. Fluconazole works best if it is taken at the same time each day. Diflucan is usually taken by mouth as a one-time only dose with or without food or as directed by your doctor. Do not stop taking Diflucan without talking to your doctor if you are allergic to it or to other antifungal drugs.
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