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The enzyme that makes prostaglandins, resulting in lower concentrations of prostaglandins. Celebrex is used to reduce pain and inflammation in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Celebrex works by blocking the action of a substance in the body by inhibiting the breakdown of Celecoxib in the body called cyclo-oxygenase. In the body by inhibiting the breakdown of Celecoxib in the liver. Celecoxib does not interfere with the clotting of blood.
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