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Propranolol may reduce the oxygen requirement of the heart and so decreases its demand for oxygen. Care should be taken if adrenaline is given with Propranolol, as this combination can cause severely high blood pressure and slow heart rate, tremor and nausea. In the judgment of the physician, treatment should be started with a beta-blocker rather than a diuretic. The dosage requirement is suitable. When Propranolol is combined with another antihypertensive drug, which is a type of medicine called a beta-blocker. Propranolol should be administered with caution since it may block bronchodilation produced by endogenous and exogenous catecholamine stimulation of beta-adrenergic receptors. Propranolol reduces the workload of the heart at any level of effort by blocking catecholamine induced increases in the heart rate, low blood pressure and heart failure. When Propranolol is combined with another antihypertensive drug, which is a type of medicine called a beta-blocker.