Drink some liquid after swallowing Topiramate to make sure the entire drug is swallowed. Treatment of migraine headaches in adults. One of the medications that have been increasingly prescribed as a migraine preventive is the antiseizure medication Topamax. Although still classified as an anticonvulsant, Topamax is mostly prescribed for the treatment of migraines and sometimes as an antidepressant. The entire drug is swallowed. Topiramate, which was originally used for seizures but now is mostly used for migraine prevention, has been found to increase a person's risk of getting kidney stones.
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